Gene information
Official symbol F2RL1
Official full name F2R like trypsin receptor 1
Gene type protein-coding gene
Chromosome5q13.3
Alias symbolPAR2
Previous symbolGPR11
Gene familyF2R receptors
Resources
Entrez Gene 2150
HGNC HGNC:3538
Ensembl ENSG00000164251
Vega OTTHUMG00000102118
UCSC uc003keo.4
GO terms: 112 records
GO Description Category LogP Number of genes Detail
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001885 endothelial cell development GO Biological Processes -5.33490415 11 More
GO:0001912 positive regulation of leukocyte mediated cytotoxicity GO Biological Processes -3.17989306 9 More
GO:0001959 regulation of cytokine-mediated signaling pathway GO Biological Processes -13.0991884 33 More
GO:0001960 negative regulation of cytokine-mediated signaling pathway GO Biological Processes -11.0318814 22 More
GO:0002064 epithelial cell development GO Biological Processes -8.05661081 27 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003014 renal system process GO Biological Processes -10.4348518 24 More
GO:0003073 regulation of systemic arterial blood pressure GO Biological Processes -22.2238525 34 More
GO:0003158 endothelium development GO Biological Processes -13.1102461 25 More
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway GO Biological Processes -11.6592522 24 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0008283 cell population proliferation GO Biological Processes -17.2298624 68 More
GO:0009615 response to virus GO Biological Processes -11.2861143 47 More
GO:0010638 positive regulation of organelle organization GO Biological Processes -6.49207636 47 More
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -15.9250248 30 More
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -18.2876323 28 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030855 epithelial cell differentiation GO Biological Processes -14.2408795 69 More
GO:0031343 positive regulation of cell killing GO Biological Processes -3.44182824 10 More
GO:0031344 regulation of cell projection organization GO Biological Processes -8.91314416 62 More
GO:0031346 positive regulation of cell projection organization GO Biological Processes -6.78114948 37 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031349 positive regulation of defense response GO Biological Processes -32.1301903 71 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032535 regulation of cellular component size GO Biological Processes -4.60941253 33 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032649 regulation of interferon-gamma production GO Biological Processes -12.4733429 27 More
GO:0032651 regulation of interleukin-1 beta production GO Biological Processes -19.7300517 34 More
GO:0032652 regulation of interleukin-1 production GO Biological Processes -24.2088254 41 More
GO:0032653 regulation of interleukin-10 production GO Biological Processes -10.1959901 18 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032682 negative regulation of chemokine production GO Biological Processes -6.18749803 9 More
GO:0032755 positive regulation of interleukin-6 production GO Biological Processes -18.6559032 31 More
GO:0032873 negative regulation of stress-activated MAPK cascade GO Biological Processes -3.60984508 9 More
GO:0032928 regulation of superoxide anion generation GO Biological Processes -6.91942497 9 More
GO:0032930 positive regulation of superoxide anion generation GO Biological Processes -6.32323278 8 More
GO:0032956 regulation of actin cytoskeleton organization GO Biological Processes -4.25470878 32 More
GO:0032970 regulation of actin filament-based process GO Biological Processes -7.72273150 43 More
GO:0034121 regulation of toll-like receptor signaling pathway GO Biological Processes -7.06389205 16 More
GO:0034123 positive regulation of toll-like receptor signaling pathway GO Biological Processes -3.90690001 7 More
GO:0034330 cell junction organization GO Biological Processes -7.96624809 49 More
GO:0035023 regulation of Rho protein signal transduction GO Biological Processes -3.55619697 12 More
GO:0035025 positive regulation of Rho protein signal transduction GO Biological Processes -2.57451150 6 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042119 neutrophil activation GO Biological Processes -4.98581398 8 More
GO:0043087 regulation of GTPase activity GO Biological Processes -2.19988031 26 More
GO:0043243 positive regulation of protein-containing complex disassembly GO Biological Processes -3.26415888 7 More
GO:0043244 regulation of protein-containing complex disassembly GO Biological Processes -2.18901367 12 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043409 negative regulation of MAPK cascade GO Biological Processes -13.5471736 35 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043547 positive regulation of GTPase activity GO Biological Processes -1.94334853 20 More
GO:0043903 regulation of biological process involved in symbiotic interaction GO Biological Processes -3.29518609 9 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044060 regulation of endocrine process GO Biological Processes -7.84992769 12 More
GO:0044089 positive regulation of cellular component biogenesis GO Biological Processes -10.7794496 56 More
GO:0045216 cell-cell junction organization GO Biological Processes -2.57190963 16 More
GO:0045446 endothelial cell differentiation GO Biological Processes -10.3072059 20 More
GO:0046328 regulation of JNK cascade GO Biological Processes -6.26985667 21 More
GO:0046329 negative regulation of JNK cascade GO Biological Processes -2.96833359 7 More
GO:0046578 regulation of Ras protein signal transduction GO Biological Processes -3.44587232 19 More
GO:0046579 positive regulation of Ras protein signal transduction GO Biological Processes -5.05172294 12 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050714 positive regulation of protein secretion GO Biological Processes -15.7339081 32 More
GO:0050764 regulation of phagocytosis GO Biological Processes -16.0793009 29 More
GO:0050926 regulation of positive chemotaxis GO Biological Processes -15.5115450 16 More
GO:0050927 positive regulation of positive chemotaxis GO Biological Processes -14.3403642 15 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051056 regulation of small GTPase mediated signal transduction GO Biological Processes -3.71798673 14 More
GO:0051057 positive regulation of small GTPase mediated signal transduction GO Biological Processes -4.49369376 12 More
GO:0051222 positive regulation of protein transport GO Biological Processes -13.8994291 46 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway GO Biological Processes -4.39154198 8 More
GO:0051493 regulation of cytoskeleton organization GO Biological Processes -3.52271067 40 More
GO:0051495 positive regulation of cytoskeleton organization GO Biological Processes -3.67944181 20 More
GO:0051607 defense response to virus GO Biological Processes -3.02916189 22 More
GO:0060491 regulation of cell projection assembly GO Biological Processes -2.36338574 17 More
GO:0060759 regulation of response to cytokine stimulus GO Biological Processes -13.7003447 35 More
GO:0060761 negative regulation of response to cytokine stimulus GO Biological Processes -10.5179624 22 More
GO:0061028 establishment of endothelial barrier GO Biological Processes -4.39154198 8 More
GO:0062207 regulation of pattern recognition receptor signaling pathway GO Biological Processes -5.69211704 17 More
GO:0062208 positive regulation of pattern recognition receptor signaling pathway GO Biological Processes -3.35916365 8 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade GO Biological Processes -3.60984508 9 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070374 positive regulation of ERK1 and ERK2 cascade GO Biological Processes -34.9831828 64 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090322 regulation of superoxide metabolic process GO Biological Processes -9.31154255 13 More
GO:0098801 regulation of renal system process GO Biological Processes -10.5008143 14 More
GO:0110053 regulation of actin filament organization GO Biological Processes -3.93783734 26 More
GO:0120032 regulation of plasma membrane bounded cell projection assembly GO Biological Processes -2.40785708 17 More
GO:0120035 regulation of plasma membrane bounded cell projection organization GO Biological Processes -8.54789693 60 More
GO:0140546 defense response to symbiont GO Biological Processes -3.00647654 22 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1902903 regulation of supramolecular fiber organization GO Biological Processes -5.63791156 37 More
GO:1902905 positive regulation of supramolecular fiber organization GO Biological Processes -5.32876142 22 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903829 positive regulation of protein localization GO Biological Processes -12.9651258 57 More
GO:1904951 positive regulation of establishment of protein localization GO Biological Processes -13.0308630 46 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
Drug-Gene interaction
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Related drugs: 8 records
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg24573501 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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